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Iron and reactive oxygen species activity in parkinsonian substantia nigra

✍ Scribed by Anna Wypijewska; Jolanta Galazka-Friedman; Erika R. Bauminger; Zbigniew K. Wszolek; Katherine J. Schweitzer; Dennis W. Dickson; Andrzej Jaklewicz; Danek Elbaum; Andrzej Friedman


Book ID
116820759
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
406 KB
Volume
16
Category
Article
ISSN
1353-8020

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Iron in parkinsonian and control substan
✍ J. GaΕ‚aΜ§zka-Friedman; E. R. Bauminger; Dr. A. Friedman; M. Barcikowska; D. Heche πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 856 KB

We used MΓΆssbauer spectroscopy to study the iron content, the redox state, and the binding site of iron in substantia nigra (SN) from parkinsonian (PD) and control brains. Measurements performed on fresh-frozen, formalin-fixed, and lyophilized samples demonstrated the presence of ferric (Fe3+) iron