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Iron and Gene Expression: Molecular Mechanisms Regulating Cellular Iron Homeostasis

✍ Scribed by Lukas C. Kühn

Book ID: 111435152
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 951 KB
Volume: 56
Category: Article
ISSN: 0029-6643
DOI: 10.1111/j.1753-4887.1998.tb01681.x

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## Abstract Iron uptake and storage are tightly regulated to guarantee sufficient iron for essential cellular processes and to prevent the production of damaging free radicals. A non‐classical class I MHC molecule, the hemochromatosis factor HFE, has been shown to regulate iron metabolism, potentia