IRF6 polymorphisms are associated with nonsyndromic orofacial clefts in a Chinese Han population
β Scribed by Yongchu Pan; Junqing Ma; Weibin Zhang; Yifei Du; Yuming Niu; Meilin Wang; Zhengdong Zhang; Lin Wang
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 161 KB
- Volume
- 152A
- Category
- Article
- ISSN
- 1552-4825
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Objectives/Hypothesis: Cleft lip with or without cleft palate (CL/P) is a common birth defect throughout the world. Linkage studies have shown interferon regulatory factor 6 (__IRF6__) to be associated with CL/P in multiple populations, including one in Honduras. It is unknown, howe
## Abstract ## Objectives/Hypothesis: Interferon regulatory factor 6 (__IRF6__), the gene that causes van der Woude syndrome (VWS), is a candidate gene for nonsyndromic cleft lip with or without cleft palate (NSCLP) because a number of studies have supported an association between NSCLP and single
BACKGROUND: Polymorphisms in genes that are involved in folic acid metabolism may be important maternal risk factors for the birth of a child with nonsyndromic cleft lip and/or palate (NSCL/P). The aim of this study was to determine the involvement of polymorphic variants in four genes (MTHFR, MTHFD
## Abstract Apurinic/apyrimidinic endonuclease 1 (APE1) is a DNA repair protein, which plays important roles in the base excision repair (BER) pathway. Genetic variations of __APE1__ have been shown to influence an individual's susceptibility to carcinogenesis. We hypothesized the genetic polymorph