IR Evidences for N -9 and N -7 Regioisomers of the Acyclic Purine Nucleoside Analogues
✍ Scribed by Rai´, Silvana; Pongraĉić, Mario; Mintas, Mladen
- Book ID
- 127127524
- Publisher
- Taylor and Francis Group
- Year
- 1997
- Tongue
- English
- Weight
- 460 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0038-7010
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Purine Nucleoside Analogues. Part 11. An Alternative Synthesis of N-and O-Alkyl Derivatives of 9-and 7-[(2-Acetoxyethoxy)methyl]-N 2 -acetylguanine. -Alkylation of the title guanines is investigated in order to find a simple method for the preparation of modified acyclovir derivatives.
Milos ˇBude ˇs ˇı ´nsky ´,[a] Radek Marek, [b] Jaromı ´r Marek, [b] and Antonı ´n Holy ´[a] Keywords: Nucleosides / Acyclic analogues / Purines / Alkylations / 15 N NMR N 7 -and N 9 -regioisomers of cyanomethyl and trifluoroethyl-order to modify their side chain. In this way, several new αbranched a