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ipso-Substitution with Sodium-N-alkyl-(p-nitrobenzene)sulfonamide. A novel anionic rearrangement

✍ Scribed by Paul Müller; Nguyen-Thi Minh Phuong


Publisher
John Wiley and Sons
Year
1979
Tongue
German
Weight
169 KB
Volume
62
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Reaction of N‐benzyl‐N, N‐di‐(p‐nitrobenzene)sulfonamide (3) with NaCN/HMPA at 140° affords N‐benzyl‐p‐nitroaniline (4). The same product is obtained upon heating of the sodium salt of N‐benzyl‐(p‐nitrobenzene)sulfonamide (5). The transformation 5 → 4 is believed to proceed via an anionic episulfonyl compound 6.