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Ipilimumab: A Guide to Its Use in Advanced Melanoma

✍ Scribed by Lyseng-Williamson, Katherine A.; Sanford, Mark

Book ID
121645303
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2012
Tongue
English
Weight
145 KB
Volume
13
Category
Article
ISSN
1175-0561

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## BACKGROUND In patients with melanoma, ipilimumab (an antibody against cytotoxic T-lymphocyteassociated antigen 4 [CTLA-4]) prolongs overall survival, and nivolumab (an antibody against the programmed death 1 [PD-1] receptor) produced durable tumor regression in a phase 1 trial. On the basis of t