We have examined the effect of the Ca2+ (Mg2+)-ATPase inhibitors thapsigargin (TG) and vanadate on ATP-dependent 45Ca2+ uptake into IP3-sensitive Ca2+ pools in isolated microsomes from rat pancreatic acinar cells. The inhibitory effect of TG was biphasic. About 40-50% of total Ca2+ uptake was inhibi
IP3receptors in cell survival and apoptosis: Ca2+release and beyond
✍ Scribed by Suresh K. Joseph; György Hajnóczky
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 520 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1360-8185
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