IP-10 Is Critical for Effector T Cell Trafficking and Host Survival in Toxoplasma gondii Infection

Intrinsic expression of Nod2 in CD4+ T l

Intrinsic expression of Nod2 in CD4+ T lymphocytes is not necessary for the development of cell-mediated immunity and host resistance to Toxoplasma gondii

✍ Braulia C. Caetano; Amlan Biswas; Djalma S. Lima-Junior; Luciana Benevides; Tiag 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB

## Abstract Nod2 belongs to the nucleotide‐binding domain leucine‐rich repeat family of proteins and senses bacterial cell wall components to initiate innate immune responses against various pathogens. Recently, it has been reported that T‐cell‐intrinsic expression of Nod2 promotes host defense aga