## Abstract ATP is the dominant messenger for astrocyteβtoβastrocyte calciumβmediated communication. Definition of the exact ATP/P2 receptors in astrocytes and of their coupling to intracellular calcium ([Ca^2+^]~i~) has important implications for brain physiology and pathology. We show that, with
β¦ LIBER β¦
Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes
β Scribed by Oleg Palygin; Ulyana Lalo; Alexei Verkhratsky; Yuriy Pankratov
- Book ID
- 113525876
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 701 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0143-4160
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## Abstract Purinergic signalling plays a major role in intercellular communication between neurons and glial cells. Glial cells express metabotropic receptors for ATP and adenosine, the latter being activated after ATP cleavage through extracellular ectoβATPase activity. Ionotropic receptors for e