The zwitterionic antihistamine cetirizine and its parent drug hydroxyzine as reference compound were examined for their 3D structures and dynamics. After attributing, by NMR spectroscopy, the two basic pK a values, the most common conformations for each electrical species were determined by molecula
Ionic Partition Diagram of the Zwitterionic Antihistamine Cetirizine
✍ Scribed by Géraldine Bouchard; Alessandra Pagliara; Georgette Plemper van Balen; Pierre-Alain Carrupt; Bernard Testa; Véronique Gobry; Hubert H. Girault; Giulia Caron; Giuseppe Ermondi; Roberta Fruttero
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- German
- Weight
- 173 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0018-019X
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