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Ion selectivity from local configurations of ligands in solutions and ion channels

โœ Scribed by D. Asthagiri; P.D. Dixit; S. Merchant; M.E. Paulaitis; L.R. Pratt; S.B. Rempe; S. Varma


Book ID
108109028
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
581 KB
Volume
485
Category
Article
ISSN
0009-2614

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Modeling of ion permeation in calcium an
โœ P.S. Raj Ganesh; Baron Chanda; S.K. Gupta; M.K. Mathew; Jayaraman Chandrasekhar ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 193 KB ๐Ÿ‘ 1 views

## Structure-function studies have shown that it is possible to convert a sodium channel to a calcium-selective channel by a single amino acid substitution in the selectivity filter locus. Ion permeation through the "model selectivity filter" was modeled with a reduced set of functional groups repr