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Ion-pair liquid chromatography of steady-state plasma levels of chlorimipramine and demethylchlorimipramine

✍ Scribed by Britt Mellström; Gunnel Tybring


Book ID
108448029
Publisher
Elsevier Science
Year
1977
Weight
709 KB
Volume
143
Category
Article
ISSN
0378-4347

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Ion-pair liquid chromatography of amitri
✍ Britt Mellström; Robin Braithwaite 📂 Article 📅 1978 🏛 Elsevier Science 🌐 English ⚖ 451 KB

A method is described for the determination of amitriptyline and nortriptyline in the plasma of patients during treatment. The method is based on liquid chromatography of the amines as ion-pairs with perchlorate. The separation column is packed with silica gel, and a mixture of diisopropyl ether, di