A new candidate reference method is presented for the determination of thyroxine in serum. The method is based on isotope dilution-liquid chromatography/tandem mass spectrometry using electrospray for ionization. The internal standard used was 13 C 6 -thyroxine, sample pretreatment consisted of prot
✦ LIBER ✦
Ion chromatography as potential reference methodology for the determination of total sodium and potassium in human serum
✍ Scribed by Linda M. Thienpont; Jean E. Van Nuwenborg; Dietmar Stöckl
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 564 KB
- Volume
- 706
- Category
- Article
- ISSN
- 1873-3778
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## Abstract A sensitive and reproducible stir bar sorptive extraction and HPLC‐UV detection method was used for the therapeutic drug monitoring of chlorpromazine and trifluoperazine in human serum. The separation was achieved using a C~18~ column. The mobile phase consisted of methanol/sodium aceta