AhStNCt Much research has been done over the years on the subject of thyreostatlc drugs of the thlouracd type m cattle fattemng These substances mcrease body we& by enlarged ftimg of the gastro-mtestmal tract and by augmented water retention On the other hand, httle work has been done on the ehmmatlon and the presence of residues of morgamc thyreostatxx such as perchlorate The ~llll of tlus study was to evaluate the ebmmatlon of ammomum perchlorate m cattle urme accordmg to the concentration gwen and the duration of admmlstration Perchlorate concentrations were measured by mobde phase ion chromatography The detection hnut was 0 1 mg kg-l for tenfold Bluted urme Keywom!s Ion chromatography, Cattle, Per&orate, Thyreostahc drugs, Unne
Thyreostatlc drugs (TS) are used to cause fraudulently mcreased we&t gam m cattle by mtibltlon of the thyroid gland The weight gain cons@s mamly of an mcreased fillmg of the gastro-mtestmal tract and augmented extracellular water retention m slaughtered ammals [ll Meat from TS-treated ammals may be exudative and thus of mfenor quahty The presence of residues of these h@y potent antlthyrold drugs 111 meat may constitute a human health hazard Therefore, the use of these drugs for cattle fattenmg IS prohlblted m the European Econonuc Commumty (EEC) Thyreostatlc drugs were commonly abused m cattle fattening m the 1970s The most frequently used substances m those days were of the thlourad type, such as methyl-, propyl-and