Ion channels in canalicular rat liver plasma membranes
โ Scribed by Sellinger, M.; Weinman, S.A.; Boyer, J.L.; Graf, J.
- Book ID
- 123387695
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 61 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0168-8278
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The purpose of this study was to provide further insight into the mechanism of bilirubin diglucuronide excretion through the hepatocyte canalicular membrane by investigating the uptake of (SH)bilirubin diglucuronide by purified canalicular membrane vesicles of rat liver. The uptake was analyzed by a
Controversy exists concerning the localization of the enzyme Na+,K+-ATPase to canalicular membranes in hepatocytes. Most studies find enzyme activity only at the basolateral plasma membrane domain of the hepatocyte. However, Na+,K+-ATPase activity has been detected recently in a canalicular membrane