✦ LIBER ✦

Ion channel redistribution and function during development of the myelinated axon

✍ Scribed by Vabnick, Ian ;Shrager, Peter

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 349 KB
Volume: 37
Category: Article
ISSN: 0022-3034
DOI: 10.1002/(sici)1097-4695(199810)37:1<80::aid-neu7>3.0.co;2-4

No coin nor oath required. For personal study only.

✦ Synopsis

The development of myelinated axerly spaced to ensure a high conduction velocity and ons represents one of the most complex interactions energy efficiency without compromising the safety facamong different cell types in the nervous system. Striking changes occur in both morphology and functor for reliable propagation. In this review, we contion in the early postnatal period. Myelination effecsider the events responsible for axon development, tively isolates electrically most of the axolemma and emphasizing the involvement of ion channels. We disdramatically alters the pathways for current flow that cuss the current state of research in this area, includare required for rapid, reliable, and efficient conducing some controversies regarding mechanisms of neution. Correspondingly, ion channels must be directed ron-glial communication.

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