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Ion channel gating: insights via molecular simulations

✍ Scribed by Oliver Beckstein; Philip C Biggin; Peter Bond; Joanne N Bright; Carmen Domene; Alessandro Grottesi; John Holyoake; Mark S.P Sansom


Book ID
117105924
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
435 KB
Volume
555
Category
Article
ISSN
0014-5793

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In a number of membrane-bound viruses, ion channels are formed by integral membrane proteins. These channel proteins include M2 from influenza A, NB from influenza B, and, possibly, Vpu from HIV-1. M2 is important in facilitating uncoating of the influenza A viral genome and is the target of amantad