✦ LIBER ✦
Iodoolefinic polypropionate building blocks from vinyl silanes with control of geometry by solvent and by neighboring group participation
✍ Scribed by Kathlyn A. Parker; Richard W. Denton
- Book ID
- 104098569
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- French
- Weight
- 339 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Iododesilylation of trisubstituted (Z)-silyl olefins proceeds with retention of geometry in hexafluoroisopropanol (HFIP) but, for unhindered cases, with inversion of geometry in DMSO. When an acyloxy substituent is positioned to participate in the reaction, the protocol consistently leads to inversion of geometry.