Iodine-mediated electrophilic cyclization of 2-alkynylbenzaldoximes leading to the formation of iodoisoquinoline N-oxides
β Scribed by Zhibao Huo; Hisamitsu Tomeba; Yoshinori Yamamoto
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- French
- Weight
- 187 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0040-4039
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## Abstract Cystine peptides are conveniently prepared from __S__βacetamidomethylβ or __S__βtritylβprotected cysteine derivatives by direct oxidation with iodine. Since the reaction proceeds through the formation of sulfenyl iodides, these highly reactive groups may substitute the indole ring of tr