𝔖 Bobbio Scriptorium
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Iodinated 1,4-Naphthoquinones.

✍ Scribed by N. V. Ivashkina; E. A. Yakovleva; I. D. Ivanchikova; A. A. Moroz; M. S. Shvartsberg


Publisher
John Wiley and Sons
Year
2006
Weight
29 KB
Volume
37
Category
Article
ISSN
0931-7597

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Using the human hepatoma cell line, HepG2, and the BALB/c mouse fibroblast cell line, 3T3, as the bioindicators in the neutral red cytotoxicity assay, the effect of hydroxyl substitution on the toxicity of 1,4naphthoquinone was studied. The sequence of potency for the quinones was 5,8-dihydroxy-1,4-

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## Abstract Thiosemicarbazones 2a–e form charge‐transfer (CT) complexes with chloranil (CHL), fluoranil (TFQ) and 2,3‐dicyano‐1,4‐naphthoquinone (DCNQ). The donors 2a–d react with 2,3‐dichloro‐5,6‐dicyano‐1,4‐benzoquinone (DDQ) to yield 3‐amino‐5‐arylthiadiazoles 7 and DDQ‐H~2~ (8). The thiosemicar