Iodinated 1,4-Naphthoquinones.
✍ Scribed by N. V. Ivashkina; E. A. Yakovleva; I. D. Ivanchikova; A. A. Moroz; M. S. Shvartsberg
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 29 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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Using the human hepatoma cell line, HepG2, and the BALB/c mouse fibroblast cell line, 3T3, as the bioindicators in the neutral red cytotoxicity assay, the effect of hydroxyl substitution on the toxicity of 1,4naphthoquinone was studied. The sequence of potency for the quinones was 5,8-dihydroxy-1,4-
## Abstract Thiosemicarbazones 2a–e form charge‐transfer (CT) complexes with chloranil (CHL), fluoranil (TFQ) and 2,3‐dicyano‐1,4‐naphthoquinone (DCNQ). The donors 2a–d react with 2,3‐dichloro‐5,6‐dicyano‐1,4‐benzoquinone (DDQ) to yield 3‐amino‐5‐arylthiadiazoles 7 and DDQ‐H~2~ (8). The thiosemicar