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Inwardly Rectifying K+ (Kir) Channels in Drosophila. A CRUCIAL ROLE OF CELLULAR MILIEU FACTORS FOR Kir CHANNEL FUNCTION

✍ Scribed by Döring, Frank (author);Wischmeyer, Erhard (author);Kühnlein, Ronald P. (author);Jäckle, Herbert (author);Karschin, Andreas (author)

Book ID: 121807931
Publisher: The American Society for Biochemistry and Molecular Biology
Year: 2002
Tongue: English
Weight: 1018 KB
Volume: 277
Category: Article
ISSN: 0021-9258
DOI: 10.1074/jbc.M202385200

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The whole-cell patch-clamp technique was used to assess the current carried by inwardly rectifying K ؉ channels (K ir ) and the resting membrane potential (RMP) during long-term culture of NG108-15 cells. Culture of this cell line in serum-free medium triggers differentiation of a type I, neuron-lik