## Abstract Urokinase‐type plasminogen activator (uPA) binds to its receptor, uPAR, on the surface of cancer cells, leading to the formation of plasmin. Rhabdomyosarcoma (RMS) cell lines secrete high levels of insulin‐like growth factor II (IGF‐II), suggesting autocrine IGFs play a major role in th
Involvement of vascular endothelial growth factor and urokinase-type plasminogen activator receptor in microvessel invasion in human colorectal cancers
✍ Scribed by Shinji Nakata; Ken-ichi Ito; Minoru Fujimori; Kiyoshi Shingū; Shoji Kajikawa; Wataru Adachi; Ikuo Matsuyama; Shin-ichi Tsuchiya; Michihiko Kuwano; Jun Amano
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- French
- Weight
- 538 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0020-7136
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
The expression of urokinase-type plasminogen activator (u-PA), its receptor (u-PAR) and metalloproteases activity were analyzed in 4 human gastric-cancer cell lines (AGS, Hs746T, SNU-1, and SNU-5), in an attempt to relate these activities to their invasive potential and tumorigenicity on the modifie