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Involvement of TNF-α in glutamate-induced apoptosis in a differentiated neuronal cell line

✍ Scribed by Jiro Kogo; Yuko Takeba; Toshio Kumai; Yasushi Kitaoka; Naoki Matsumoto; Satoki Ueno; Shinichi Kobayashi


Book ID
113502226
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
604 KB
Volume
1122
Category
Article
ISSN
0006-8993

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## Abstract Transporter‐mediated glutamate uptake is a principal function of astrocytes. Our previous studies have shown that this process is compromised under hypoxic conditions through the NF‐κB mediated inhibition of expression of the glutamate transporters EAAT‐1 and EAAT‐2. Here, we demonstrat