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Involvement of the transcription factor twist in phenotype alteration through epithelial–mesenchymal transition in lung cancer cells

✍ Scribed by Harunori Nakashima; Naozumi Hashimoto; Daisuke Aoyama; Takashi Kohnoh; Koji Sakamoto; Masaaki Kusunose; Kazuyoshi Imaizumi; Yoshihiro Takeyama; Mitsuo Sato; Tsutomu Kawabe; Yoshinori Hasegawa

Book ID: 112142287
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 494 KB
Volume: 51
Category: Article
ISSN: 0899-1987
DOI: 10.1002/mc.20802

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## Abstract Epithelial cancer cells are likely to undergo epithelial–mesenchymal transition (EMT) prior to entering the peripheral circulation. By undergoing EMT, circulating tumor cells (CTCs) lose epithelial markers and may escape detection by conventional methods. Therefore, we conducted a pilot