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Involvement of the mitochondrion-dependent pathway and oxidative stress in the apoptosis of murine splenocytes induced by areca nut extract

โœ Scribed by Chia-Chi Wang; Tsung-Yun Liu; Chiung-Hsiang Cheng; Tong-Rong Jan


Book ID
116920013
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
717 KB
Volume
23
Category
Article
ISSN
0887-2333

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## Abstract Unconjugated bilirubin (UCB), the end product of heme catabolism, causes apoptosis in cells of the central nervous system, endothelial cells, and hepatotoma cells. However, the molecular mechanisms that contribute to UCB cytotoxicity remain unclear. The purpose of this study was to char