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Involvement of the locus coeruleus in analgesic effects of a low dose of naloxone during the inflammatory process

✍ Scribed by M. Tsuruoka; W. D. Willis


Publisher
Springer-Verlag
Year
1998
Tongue
English
Weight
305 KB
Volume
119
Category
Article
ISSN
0014-4819

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Naloxone HCl (10 micrograms/0.5 ml) was injected in the locus coeruleus (LC) of morphine-dependent rats and the behavioural manifestations of morphine withdrawal and the cortical levels of 3-methoxy-4-hydroxyphenylethyleneglycol sulfate (MHPG-SO4) were measured 30 min later. Naloxone precipitated a