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Involvement of the extracellular signal-regulated protein kinase pathway in phosphorylation of p53 protein and exerting cytotoxicity in human neuroblastoma cells (SH-SY5Y) exposed to acrylamide

✍ Scribed by Takeo Okuno; Masato Matsuoka; Tomoyuki Sumizawa; Hideki Igisu

Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
401 KB
Volume
80
Category
Article
ISSN
0340-5761

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The role of protein kinase C activation in changes in muscarinic receptor functions and in the appearance of biochemical properties characteristic of neuronal cells was studied in SH-SY5Y human neuroblastoma cells induced to differentiate with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (