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Involvement of the endosomal autoantigen EEA1 in homotypic fusion of early endosomes

✍ Scribed by Ian G. Mills; Arwyn T. Jones; Michael J. Clague

Book ID
114320456
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
221 KB
Volume
8
Category
Article
ISSN
0960-9822

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## Abstract Association of early endosomal autoantigen 1 (EEA1) with macropinosomes was examined in EGF‐stimulated A431 cells by dual labeling with immunofluorescence of anti‐EEA1 and FITC‐dextran (FDx), a fluid‐phase endocytic marker. Addition of EGF to A431 cells drastically enhanced macropinosom