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Involvement of signaling molecules in the prediction of response to imatinib treatment in metastatic GIST patients

✍ Scribed by Marcus Valadão; Danielle Braggio; Anna Flávia Santos; Haynna Kimie Pimenta-Inada; Eduardo Linhares; Rinaldo Gonçalves; Sérgio Romano; Bruno Vilhena; Isabele Small; Daniel Cubero; Felipe Cruz; Antônio Talvane Oliveira; Olga Martinho; Rui Manuel Reis; Denise Peixoto Guimarães; Carlos Gil Ferreira


Book ID
118481443
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
772 KB
Volume
178
Category
Article
ISSN
0022-4804

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## Abstract Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract. Long‐term survival of patients with metastatic disease has only been observed in patients with completely resected disease. Recently, the tyrosine kinase inhibitor imatinib has b