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Involvement of serum mannan binding proteins and mannose receptors in uptake of mannosylated liposomes by macrophages

✍ Scribed by P Opanasopit; Y Higuchi; S Kawakami; F Yamashita; M Nishikawa; M Hashida


Book ID
117047789
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
597 KB
Volume
1511
Category
Article
ISSN
0005-2736

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## Abstract The human immunodeficiency virus (HIV) is an enveloped virus whose surface glycoprotein gp120 binds CD4 on target cell membranes to initiate infection. About half of the carbohydrates on gp120are terminally mannosylated, a pattern common to many pathogens. We have examined the ability o