## Abstract ## Objective To test the hypotheses that 1) proinflammatory cytokines affect osteoprotegerin (OPG) and soluble receptor activator of nuclear factor κB ligand (sRANKL) production and therefore the OPG and sRANKL levels differ in rheumatoid arthritis (RA) patients in comparison with heal
Involvement of receptor activator of NFκB ligand and tumor necrosis factor-α in bone destruction in rheumatoid arthritis
✍ Scribed by E Romas; M.T Gillespie; T.J Martin
- Book ID
- 117807560
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 133 KB
- Volume
- 30
- Category
- Article
- ISSN
- 8756-3282
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Objective To investigate the roles of MAPKs and NF‐κB in tumor necrosis factor α (TNFα)–induced expression of vascular cell adhesion molecule 1 (VCAM‐1) in human rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods Human RASFs were isolated from synovial tissue obtained f
## Abstract ## Objective Increasing evidence indicates that RhoA may play a central role in the inflammatory response. This study was conducted to examine the role of RhoA in mediating the activation of NF‐κB in tumor necrosis factor α (TNFα)–stimulated rheumatoid synoviocytes, and to evaluate the