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Involvement of protein trafficking in deprenyl-induced α-secretase activity regulation in PC12 cells

✍ Scribed by Hong-Qi Yang; Zhi-Kun Sun; Mao-Wen Ba; Jun Xu; Ying Xing

Book ID
113588184
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
1015 KB
Volume
610
Category
Article
ISSN
0014-2999

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## Abstract Although the clinical effects of antipsychotics have been extensively studied, the molecular mechanisms underlying their antipsychotic activity are unclear. Chronic clozapine has been reported to reduce significantly the expression of tyrosine hydroxylase (TH) in the mesolimbic system.