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Involvement of Protein Kinase C-Regulated Ceramide Generation in Inostamycin-Induced Apoptosis

✍ Scribed by Makoto Kawatani; Siro Simizu; Hiroyuki Osada; Minoru Takada; Nadir Arber; Masaya Imoto


Book ID
115603783
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
300 KB
Volume
259
Category
Article
ISSN
0014-4827

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## Abstract Syndecans are proteoglycans that act as signaling molecules. Previously, we showed that syndecan‐2 (SYND2) is involved in the control of osteoblastic (OB) cell apoptosis. Here, we show a novel functional interaction between SYND2 and protein kinase C δ (PKCδ). Overexpression of SYND2 in