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Involvement of prostaglandin E2 synthesis in the intestinal secretory action of Escherichia coli heat-stable enterotoxin II

✍ Scribed by Yoshio Fujii; Yukiko Kondo; Keinosuke Okamoto


Book ID
109320689
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
685 KB
Volume
130
Category
Article
ISSN
0378-1097

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Lack of guanylyl cyclase C, the receptor
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## Abstract Guanylyl cyclase C (GC‐C), a transmembrane receptor for bacterial heat‐stable enterotoxin and the mammalian peptides guanylin and uroguanylin, mediates intestinal ion secretion and affects intestinal cell growth via cyclic GMP signaling. In intestinal tumors, GC‐C expression is maintain