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Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease

✍ Scribed by Pablo Garrido-Gil; Belen Joglar; Ana I Rodriguez-Perez; Maria J Guerra; Jose L Labandeira-Garcia

Book ID
115022158
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
931 KB
Volume
9
Category
Article
ISSN
1742-2094

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✍ Naomi P. Visanji; Rob M.A. de Bie; Tom H. Johnston; Andrew C. McCreary; Jonathan 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 540 KB

## Abstract The anti‐parkinsonian and levodopa‐sparing potential of the nociceptin/orphanin FQ receptor (NOP) antagonist J‐113397 has been demonstrated in rodent models of Parkinson's disease. Here, we describe the levodopa‐sparing potential of J‐113397 in MPTP‐lesioned marmosets. Coadministration