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Involvement of PKCα in insulin-induced PKCδ expression: Importance of SP-1 and NFκB transcription factors

✍ Scribed by Miriam Horovitz-Fried; Sanford R. Sampson

Book ID: 116293907
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 474 KB
Volume: 352
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2006.10.149

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## Abstract ## Objective To investigate the roles of MAPKs and NF‐κB in tumor necrosis factor α (TNFα)–induced expression of vascular cell adhesion molecule 1 (VCAM‐1) in human rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods Human RASFs were isolated from synovial tissue obtained f