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Involvement of phosphatidylinositol-3 kinase–Akt and nuclear factor kappa-B pathways in the effect of frutalin on human lymphocyte

✍ Scribed by Aline C. Brando-Lima; Roberta F. Saldanha-Gama; Cristiane Ribeiro Pereira; Christina Gaspar Villela; André Luiz Franco Sampaio; Ana C.O. Monteiro-Moreira; Maria das Graças M.O. Henriques; Renato A. Moreira; Christina Barja-Fidalgo


Book ID
116575883
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
167 KB
Volume
6
Category
Article
ISSN
1567-5769

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Regulation of phosphatidylinositol 3-kin
✍ Charu Dogra; Harish Changotra; Jon E. Wergedal; Ashok Kumar 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 472 KB

## Abstract Phosphatidylinositol 3‐kinase (PI3K)/Akt and nuclear factor‐kappa B (NF‐κB) signaling pathways play a critical role in mediating survival signals. In this study we have investigated how loss of dystrophin (the primary cause of Duchenne muscular dystrophy) modulates the activation of PI3