Involvement of Phosphatidylinositide 3′-Kinase and Rac in Platelet-Derived Growth Factor-Induced Actin Reorganization and Chemotaxis
✍ Scribed by Roya Hooshmand-Rad; Lena Claesson-Welsh; Stefan Wennström; Koutaro Yokote; Agneta Siegbahn; Carl-Henrik Heldin
- Book ID
- 115602738
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 634 KB
- Volume
- 234
- Category
- Article
- ISSN
- 0014-4827
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📜 SIMILAR VOLUMES
Previously we showed a rapid and transient inhibition of gap junctional communication (GJC) by platelet-derived growth factor (PDGF) in T51B rat liver epithelial cells expressing wild-type platelet-derived growth factor b receptors (PDGFrb). This action of PDGF correlated with the hyperphosphorylati
Platelet-derived growth factor (PDGF) and other agents that activate protein kinase C (PKC) rapidly alter cytosolic pH (pHJ and intracellular free calcium (Ca' +I,) in BALBk-3T3 fibroblasts. To define whether changes in pH, or [Ca++], are linked to PDGF-stimulated mitogenesis, these parameters were