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Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells

✍ Scribed by Basant Kumar Thakur; Tino Dittrich; Prakash Chandra; Annette Becker; Wolfgang Kuehnau; Jan-Henning Klusmann; Dirk Reinhardt; Karl Welte

Book ID
115556509
Publisher
John Wiley and Sons
Year
2012
Tongue
French
Weight
608 KB
Volume
132
Category
Article
ISSN
0020-7136

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## Abstract A range of cell types of mesenchymal origin express α‐smooth muscle actin (α‐SMA), a protein that plays a key role in controlling cell motility and differentiation along the fibrocyte and myofibroblast lineages. Although α‐SMA is often expressed in stromal cells associated to a variety