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Involvement of p53 in gemcitabine mediated cytotoxicity and radiosensitivity in breast cancer cell lines

โœ Scribed by Sameer D. Salem; Faisal M. Abou-Tarboush; Nadeem M. Saeed; Waheeb D. Al-Qadasi; M. Abul Farah; Muneera Al-Buhairi; Najla Al-Harbi; Ibrahim Alhazza; Ghazi Alsbeih


Book ID
116508752
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
684 KB
Volume
498
Category
Article
ISSN
0378-1119

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P53 mediated regulation of metallothione
โœ Elena A. Ostrakhovitch; Per-Erik Olsson; Jonas von Hofsten; M. George Cherian ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 364 KB

## Abstract Recent studies have shown that only breast cancer epithelial cells with intact p53 can induce metallothionein (MT) synthesis after exposure to metals. In this study, the potential role of p53 on regulation of MT was investigated. Results demonstrate that zinc and copper increased metal