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Involvement of p44/42 mitogen-activated protein kinases in regulating angiotensin II- and endothelin-1-induced contraction of rat thoracic aorta

โœ Scribed by Akira Ishihata; Katsunari Tasaki; Yumi Katano


Book ID
114014820
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
385 KB
Volume
445
Category
Article
ISSN
0014-2999

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## Abstract Using spontaneously hypertensive and aortic banded rats, we have shown that expression of myocardial osteopontin, an extracellular matrix protein, coincides with the development of heart failure and is inhibited by captopril, suggesting a role for angiotensin II (ANG II). This study tes