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Involvement of nitric oxide in nitroprusside-induced hepatocyte cytotoxicity

✍ Scribed by Hossein Niknahad; Peter J. O'Brien


Book ID
115784705
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
1008 KB
Volume
51
Category
Article
ISSN
0006-2952

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Galactosamine hepatotoxicity in vivo has long been associated with rapid and extensive depletion of hepatic uridine nucleotides. Depletion of uridine nucleotides is considered to be causal in the toxicity, as evidenced by the protective effect of uridine administration. However, the exact mechanism