Involvement of nipple and areola in early breast cancer

✍ Scribed by Tadaoki Morimoto; Kansei Komaki; Kozo Inui; Atsushi Umemoto; Hiroyuki Yamamoto; Kunihiko Harada; Kenji Inoue

• Publisher: John Wiley and Sons
• Year: 1985
• Tongue: English
• Weight: 353 KB
• Volume: 55
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(19850515)55:10<2459::aid-cncr2820551025>3.0.co;2-l

✦ Synopsis

In 141 mastectomy specimens, performed for invasive or noninvasive carcinomas, histopathologic study was performed to assess the extent of nipple-areola involvement by the tumor. In this study, patients were excluded if (1) the tumor was located beneath the areola; and (2) nipple and/or areola abnormalities were clinically present. Tumor involvement of the nipple and/or areola was found in 44 of 141 specimens (31%), with intraductal growth in 36 (82%) of 44, stromal invasion in 3 (7%), and ductal and stromal invasion in 5 (11%). Analysis of nipple-areolar involvement with consideration of the different variables indicates that it occurred in association with tumor size, tumor-areola distance, and histologic type. Such information provides clinically relevant guidelines in decision making for limited breast surgery.