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✦   LIBER   ✦

Involvement of NF-κB signalling in skin physiology and disease

✍ Scribed by Susanne Bell; Klaus Degitz; Martina Quirling; Nikolaus Jilg; Sharon Page; Korbinian Brand

Book ID
114283754
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
127 KB
Volume
15
Category
Article
ISSN
0898-6568

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## Abstract Binding of tumor necrosis factor‐α (TNF‐α) to its receptor activates IKK complex, which leads to inducement of NF‐κB activity. Here we report that activation of Mpl ligand is also linked to IKK and NF‐κB activity. Mpl ligand, also known as thrombopoietin (TPO) or megakaryocyte growth an