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Involvement of NF-κB in the induction of NAD(P)H: Quinone oxidoreductase (DT-diaphorase) by hypoxia, oltipraz and mitomycin C

✍ Scribed by Kang-Shen Yao; Peter J. O'Dwyer


Book ID
115783748
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
816 KB
Volume
49
Category
Article
ISSN
0006-2952

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NF-κB and AP-1 are key signaling pathway
✍ Hesham M. Korashy; Ayman O. S. El-Kadi 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB

## Abstract We have previously shown that Hg^2+^, Pb^2+^, and Cu^2+^, significantly modulate the expression of NAD(P):quinone oxidoreductase 1 (Nqo1) in Hepa 1c1c7 cells through oxidative stress‐dependent mechanisms. In the current study, we examined the role of redox‐sensitive transcription factor