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Involvement of Na+ and Ca2+ channel activation and resultant nitric oxide synthesis in glutamate-mediated hypoxic injury in rat cerebrocortical slices

✍ Scribed by Michiko Oka; Yoshinori Itoh; Yojiro Ukai


Book ID
117172566
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
363 KB
Volume
67
Category
Article
ISSN
0024-3205

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re