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Involvement of Multiple Protein Kinases in CD3-Mediated Activation of Human T Lymphocytes

✍ Scribed by Francesca Chiaffarino; Mauro Biffi; Anna Luciano; Gianni Gromo; Flavio Leoni


Book ID
112238846
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
448 KB
Volume
153
Category
Article
ISSN
0008-8749

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Occupancy of the B cell glycoprotein, CD72 results in syk-independent activation of phospholipase-C + and calcium mobilization. The cytoplasmic tail of CD72 does not contain an immunoreceptor tyrosine-based activation motif to directly transduce signals into the B lymphocyte. Hence, we investigated