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Involvement of Multidrug Resistance Associated Protein 1 (Mrp1) in the Efflux Transport of 17β Estradiol-D-17β-Glucuronide (E217βG) Across the Blood-Brain Barrier

✍ Scribed by Daisuke Sugiyama; Hiroyuki Kusuhara; Yong-Joo Lee; Yuichi Sugiyama

Book ID
111553418
Publisher
Springer US
Year
2003
Tongue
English
Weight
120 KB
Volume
20
Category
Article
ISSN
0724-8741

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Do multidrug resistance-associated prote
Do multidrug resistance-associated protein-1 and -2 play any role in the elimination of estradiol-17β-glucuronide and 2,4-dinitrophenyl-S-glutathione across the blood–cerebrospinal fluid barrier?
✍ Young-Joo Lee; Hiroyuki Kusuhara; Yuichi Sugiyama 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 140 KB

The purpose of this study was to examine the role of multidrug resistanceassociated protein-1 and -2 (Mrp1 and Mrp2) in the efflux transport of organic anions across the blood-cerebrospinal fluid (CSF) barrier. The CSF concentration of estradiol-17b-glucuronide (E 2 17bG) and 2,4-dinitrophenyl-S-glu