✦ LIBER ✦

Involvement of mixed function oxidase systems in polychlorinated biphenyl metabolism by plant cells

✍ Scribed by Incheol Lee; John S. Fletcher

Publisher: Springer
Year: 1992
Tongue: English
Weight: 354 KB
Volume: 11
Category: Article
ISSN: 0721-7714
DOI: 10.1007/bf00235262

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✦ Synopsis

Nineteen different polychlorinated biphenyl (PCB) congeners ranging in chlorine content from 2 to 6 chlorine atoms were provided to nonphotosynthetic suspension cultures of rose (Rosa sp. cv. Paul's Scarlet). After a 96 h incubation period, 11 individual congeners had been metabolized by > 10%. Provision of mixed function oxidase inhibitors (10 mM metyrapone or 0.5 mM 7,8-benzoflavone) either stopped or severely reduced the metabolism of individual congeners; whereas (inhibitors of peroxidase) (1 mM benzoate or 1 mM n-propylgallate) had minimal influence on PCB metabolism. The metabolism of PCBs by rose cultures appears to be catalyzed by a cytochrome P-450-and/or P-448-dependent enzyme system.

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