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Involvement of mitochondrial aggregation in arsenic trioxide (As2O3)-induced apoptosis in human glioblastoma cells

✍ Scribed by Naomi Haga; Naoya Fujita; Takashi Tsuruo


Book ID
108583555
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
356 KB
Volume
96
Category
Article
ISSN
1347-9032

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## Abstract The purpose of this study was to evaluate the possible involvement of the phosphoinositide 3‐kinase (PI3K)/Akt survival pathway in determining resistance to arsenic trioxide (As~2~O~3~)‐induced apoptosis. We employed a HL60 cell clone (HL60AR) with a constitutively active PI3K/Akt survi